4-Ethylaniline → HCID 49804518, compound

HRID 2194063Notes

Reaction equation

HRID 2194063 reaction equation
C(O[C:4]([C:6]1([CH2:12][CH2:13]OC)[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])C.[I:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[S:23](Cl)(=[O:25])=[O:24].[CH2:27]([C:29]1[CH:35]=[CH:34][C:32]([NH2:33])=[CH:31][CH:30]=1)[CH3:28]>>[CH2:27]([C:29]1[CH:35]=[CH:34][C:32]([N:33]2[CH2:13][CH2:12][C:6]3([CH2:7][CH2:8][N:9]([S:23]([C:18]4[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=4[I:16])(=[O:25])=[O:24])[CH2:10][CH2:11]3)[C:4]2=[O:5])=[CH:31][CH:30]=1)[CH3:28]

Participants

4

Reactant 3

HCID 115044-EthylanilineHCID 6274002-Iodobenzene-1-sulfonyl chlorideHCID 567539694-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 49804518HCID 49804518, compound

Procedure

Amorphous brown solid. MS (ESI) 525.07 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), 2-Iodo-benzenesulfonyl chloride and 4-(ethyl)-aniline.

Sources & evidence

ORD record
ord-c000e34c93a4400baaaf0fd81abe7af5
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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