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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194066Generated: October 30, 2026

4-(2,2,2-Trifluoroethoxy)aniline → HCID 49800226, compound

https://huagongshe.com/reaction/2194066

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2,2,2-Trifluoroethoxy)anilineHCID 2777119—
Reactant2-(Trifluoromethoxy)benzene-1-sulfonyl chlorideHCID 2777215—
Reactant4-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl esterHCID 56753969—
ProductHCID 49800226HCID 49800226—

Reaction Steps

Brown solid. MS (ESI): 553.12 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), 2-trifluoromethoxy-benzenesulfonyl chloride and 4-(2,2,2-trifluoro-ethoxy)-phenylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08329904B2
Source datasetuspto-grants-2012_12
ORD IDord-54ad5560f35d41dcbc723b929bb2177a
Source noteuspto-grants-2012_12