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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194069Generated: October 30, 2026

2-(Trifluoromethoxy)benzene-1-sulfonyl chloride → HCID 49800501, compound

https://huagongshe.com/reaction/2194069

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethoxy)benzene-1-sulfonyl chlorideHCID 2777215—
Reactant4-CyclopropylanilineHCID 12253927—
Reactant4-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl esterHCID 56753969—
ProductHCID 49800501HCID 49800501—

Reaction Steps

Off-white solid. MS (ESI): 495.15 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), 2-trifluoromethoxy-benzenesulfonyl chloride and 4-(cyclopropyl)-aniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08329904B2
Source datasetuspto-grants-2012_12
ORD IDord-b4adfd06757d40e8b1aa95c7afa79710
Source noteuspto-grants-2012_12