4-Aminostyrene → HCID 49801072, compound

HRID 2194077Notes

Reaction equation

HRID 2194077 reaction equation
C(O[C:4]([C:6]1([CH2:12][CH2:13]OC)[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])C.[Cl:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[S:23](Cl)(=[O:25])=[O:24].[NH2:27][C:28]1[CH:35]=[CH:34][C:31]([CH:32]=[CH2:33])=[CH:30][CH:29]=1>>[Cl:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[S:23]([N:9]1[CH2:8][CH2:7][C:6]2([C:4](=[O:5])[N:27]([C:28]3[CH:35]=[CH:34][C:31]([CH:32]=[CH2:33])=[CH:30][CH:29]=3)[CH2:13][CH2:12]2)[CH2:11][CH2:10]1)(=[O:25])=[O:24]

Participants

4

Reactant 3

HCID 737004-AminostyreneHCID 761872-Chlorobenzenesulfonyl chlorideHCID 567539694-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 49801072HCID 49801072, compound

Procedure

White solid. MS (ESI): 431.3 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), 2-chloro-benzenesulfonyl chloride and 4-amino-styrene.

Sources & evidence

ORD record
ord-a93c36c955724639a1783ab0ad2de142
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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