4-Isopropoxyaniline → HCID 49801073, compound

HRID 2194078Notes

Reaction equation

HRID 2194078 reaction equation
C(O[C:4]([C:6]1([CH2:12][CH2:13]OC)[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])C.[CH:16]1([CH2:20][S:21](Cl)(=[O:23])=[O:22])[CH2:19][CH2:18][CH2:17]1.[CH:25]([O:28][C:29]1[CH:35]=[CH:34][C:32]([NH2:33])=[CH:31][CH:30]=1)([CH3:27])[CH3:26]>>[CH:16]1([CH2:20][S:21]([N:9]2[CH2:8][CH2:7][C:6]3([C:4](=[O:5])[N:33]([C:32]4[CH:31]=[CH:30][C:29]([O:28][CH:25]([CH3:27])[CH3:26])=[CH:35][CH:34]=4)[CH2:13][CH2:12]3)[CH2:11][CH2:10]2)(=[O:23])=[O:22])[CH2:19][CH2:18][CH2:17]1

Participants

4

Reactant 3

HCID 821124-IsopropoxyanilineHCID 55280140Cyclobutylmethanesulfonyl chlorideHCID 567539694-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 49801073HCID 49801073, compound

Procedure

Light brown solid. MS (ESI): 421.21 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), cyclobutyl-methanesulfonyl chloride, 4-isopropoxy-aniline.

Sources & evidence

ORD record
ord-6af306615a7743cc8150014595ac430b
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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