4-Isopropoxyaniline → HCID 49801076, compound

HRID 2194081Notes

Reaction equation

HRID 2194081 reaction equation
C(O[C:4]([C:6]1([CH2:12][CH2:13]OC)[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])C.[CH:16]1([S:19](Cl)(=[O:21])=[O:20])[CH2:18][CH2:17]1.[CH:23]([O:26][C:27]1[CH:33]=[CH:32][C:30]([NH2:31])=[CH:29][CH:28]=1)([CH3:25])[CH3:24]>>[CH:16]1([S:19]([N:9]2[CH2:8][CH2:7][C:6]3([C:4](=[O:5])[N:31]([C:30]4[CH:29]=[CH:28][C:27]([O:26][CH:23]([CH3:25])[CH3:24])=[CH:33][CH:32]=4)[CH2:13][CH2:12]3)[CH2:11][CH2:10]2)(=[O:21])=[O:20])[CH2:18][CH2:17]1

Participants

4

Reactant 3

HCID 821124-IsopropoxyanilineHCID 2760919Cyclopropanesulfonyl chlorideHCID 567539694-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 49801076HCID 49801076, compound

Procedure

Off-white solid. MS (ESI): 393.18 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), cyclopropanesulfonyl chloride, 4-isopropoxy-aniline.

Sources & evidence

ORD record
ord-069c6095cfa84033b705d3bd3725b077
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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