2-Chlorobenzenesulfonyl chloride → HCID 59577956, compound

HRID 2194109Notes

Reaction equation

HRID 2194109 reaction equation
C(O[C:4]([C:6]1([CH2:12][CH2:13]OC)[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5])C.[Cl:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[S:23](Cl)(=[O:25])=[O:24].[CH3:27][C:28]1[S:29][C:30]2[CH:36]=[C:35]([NH2:37])[CH:34]=[CH:33][C:31]=2[N:32]=1>>[Cl:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[S:23]([N:9]1[CH2:8][CH2:7][C:6]2([C:4](=[O:5])[N:37]([C:35]3[CH:34]=[CH:33][C:31]4[N:32]=[C:28]([CH3:27])[S:29][C:30]=4[CH:36]=3)[CH2:13][CH2:12]2)[CH2:11][CH2:10]1)(=[O:25])=[O:24]

Participants

4

Reactant 3

HCID 761872-Chlorobenzenesulfonyl chlorideHCID 7628312-methylbenzo[d]thiazol-6-amineHCID 567539694-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 59577956HCID 59577956, compound

Procedure

Light yellow crystalline solid. MS (ESI): 476.1 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), 2-chlorobenzenesulfonyl chloride and 2-methyl-benzothiazol-6-ylamine.

Sources & evidence

ORD record
ord-ef85f5271c434e6f88cd404bc3d54a94
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

Loading…