HCID 62056677, compound → HCID 59578100, compound

HRID 2194120Notes

Reaction equation

HRID 2194120 reaction equation
[CH3:1][C:2]([CH3:9])([CH3:8])[CH2:3][S:4](Cl)(=[O:6])=[O:5].C(O[C:13]([C:15]1([CH2:21][CH2:22]OC)[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]1)=[O:14])C.[F:25][C:26]([F:38])([F:37])[CH2:27][CH2:28][O:29][C:30]1[CH:35]=[CH:34][C:33]([NH2:36])=[CH:32][CH:31]=1>>[CH2:3]([S:4]([N:18]1[CH2:17][CH2:16][C:15]2([C:13](=[O:14])[N:36]([C:33]3[CH:34]=[CH:35][C:30]([O:29][CH2:28][CH2:27][C:26]([F:25])([F:37])[F:38])=[CH:31][CH:32]=3)[CH2:22][CH2:21]2)[CH2:20][CH2:19]1)(=[O:6])=[O:5])[C:2]([CH3:9])([CH3:8])[CH3:1]

Participants

3

Reactant 2

HCID 62056677HCID 62056677, compoundHCID 86647652HCID 86647652, compound

Product 1

HCID 59578100HCID 59578100, compound

Procedure

This material was prepared according to example 1 steps C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester 2,2-dimethyl-propane-1-sulfonyl chloride, 4-(3,3,3-trifluoro-propoxy)-phenylamine as white solid. MS (ESI): 477.2 (MH+).

Workup

  1. customThis material was prepared

Sources & evidence

ORD record
ord-385988ad0ce94bd38932442c0be2053d
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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