8-(2-Chloro-benzenesulfonyl)-2,8-diaza-spiro[4.5]decan-1-one → HCID 59578047, compound

HRID 2194132Notes

Reaction equation

HRID 2194132 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([N:11]1[CH2:21][CH2:20][C:14]2([C:18](=[O:19])[NH:17][CH2:16][CH2:15]2)[CH2:13][CH2:12]1)(=[O:10])=[O:9].[CH2:22]([O:24][CH2:25][C:26]1[CH:31]=[CH:30][C:29](I)=[CH:28][CH:27]=1)[CH3:23]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([N:11]1[CH2:21][CH2:20][C:14]2([C:18](=[O:19])[N:17]([C:29]3[CH:30]=[CH:31][C:26]([CH2:25][O:24][CH2:22][CH3:23])=[CH:27][CH:28]=3)[CH2:16][CH2:15]2)[CH2:13][CH2:12]1)(=[O:9])=[O:10]

Participants

3

Reactant 2

HCID 595779948-(2-Chloro-benzenesulfonyl)-2,8-diaza-spiro[4.5]decan-1-oneHCID 65488938HCID 65488938, compound

Product 1

HCID 59578047HCID 59578047, compound

Procedure

This material was prepared in analogy to example 148 step F) from 8-(2-chloro-benzenesulfonyl)-2,8-diaza-spiro[4.5]decan-1-one and 1-ethoxymethyl-4-iodo-benzene (for synthesis: M. Schamchal et al; J. Gen. Chem. USSR (Engl. Transl.); 34; 1964; 1830). White solid. MS (ESI): 463.2 MH+).

Sources & evidence

ORD record
ord-c48dd97c0dc5414ea394e81ab0e0bf65
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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