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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194134Generated: October 25, 2026

1-(4-Iodophenyl)ethan-1-one → 2-(4-Acetyl-phenyl)-8-(2-chloro-benzenesulfonyl)-2,8-diaza-spiro[4.5]decan-1-one

https://huagongshe.com/reaction/2194134

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Iodophenyl)ethan-1-oneHCID 72869—
Reactant8-(2-Chloro-benzenesulfonyl)-2,8-diaza-spiro[4.5]decan-1-oneHCID 59577994—
Product2-(4-Acetyl-phenyl)-8-(2-chloro-benzenesulfonyl)-2,8-diaza-spiro[4.5]decan-1-oneHCID 59577963—

Reaction Steps

This material was prepared in analogy to example 148 step F) from 8-(2-chloro-benzenesulfonyl)-2,8-diaza-spiro[4.5]decan-1-one and 1-(4-iodo-phenyl)-ethanone. White solid. MS (ESI): 447.1 MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08329904B2
Source datasetuspto-grants-2012_12
ORD IDord-29c4deb313db405095a4cd70cbcf663e
Source noteuspto-grants-2012_12