Benzene, 1-iodo-4-(trifluoromethyl)- → HCID 59578090, compound

HRID 2194140Notes

Reaction equation

HRID 2194140 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([N:11]1[CH2:22][CH2:21][C:14]2([C:19](=[O:20])[NH:18][CH2:17][CH2:16][CH2:15]2)[CH2:13][CH2:12]1)(=[O:10])=[O:9].I[C:24]1[CH:29]=[CH:28][C:27]([C:30]([F:33])([F:32])[F:31])=[CH:26][CH:25]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([N:11]1[CH2:22][CH2:21][C:14]2([C:19](=[O:20])[N:18]([C:24]3[CH:29]=[CH:28][C:27]([C:30]([F:33])([F:32])[F:31])=[CH:26][CH:25]=3)[CH2:17][CH2:16][CH2:15]2)[CH2:13][CH2:12]1)(=[O:9])=[O:10]

Participants

3

Reactant 2

HCID 67993Benzene, 1-iodo-4-(trifluoromethyl)-HCID 66788091HCID 66788091, compound

Product 1

HCID 59578090HCID 59578090, compound

Procedure

This material was prepared in analogy to example 148 step F) from 9-(2-chloro-benzenesulfonyl)-2,9-diaza-spiro[5.5]undecan-1-one and 1-iodo-4-trifluoromethyl-benzene. White solid. MS (ESI): 487.1 MH+).

Sources & evidence

ORD record
ord-e05b532bee82450884c3a362042c07e8
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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