HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-iodo-4-(trifluoromethyl)- → 8-(3,5-Dimethyl-isoxazole-4-sulfonyl)-2-(4-trifluoromethyl-phenyl)-2,8-diaza-spiro[4.5]decan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-iodo-4-(trifluoromethyl)- | HCID 67993 | — |
| Reactant | 8-(3,5-Dimethyl-isoxazole-4-sulfonyl)-2,8-diaza-spiro[4.5]decan-1-one | HCID 59577900 | — |
| Product | 8-(3,5-Dimethyl-isoxazole-4-sulfonyl)-2-(4-trifluoromethyl-phenyl)-2,8-diaza-spiro[4.5]decan-1-one | HCID 59577920 | — |
Reaction Steps
This material was prepared according to example 162 step B) from 8-(3,5-dimethyl-isoxazole-4-sulfonyl)-2,8-diaza-spiro[4.5]decan-1-one and 1-iodo-4-trifluoromethyl-benzene. Off white solid. MS (ESI): 458.13 MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329904B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-45d7240adedc49e6b7f52eee18687476 |
| Source note | uspto-grants-2012_12 |