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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194185Generated: November 3, 2026

Methanesulfonyl chloride → 8-Methanesulfonyl-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one

https://huagongshe.com/reaction/2194185

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonyl chlorideHCID 31297—
Reactant2-(4-(Trifluoromethoxy)phenyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 66742759—
Product8-Methanesulfonyl-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-oneHCID 59577949—

Reaction Steps

The title compound was prepared in analogy to example 180 step D from 2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one (described in example 180 step C) and methanesulfonyl chloride. White solid. MS (ESI): 393.2 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08329904B2
Source datasetuspto-grants-2012_12
ORD IDord-713a9d3fe6a24b3393df27c1bf9dd6eb
Source noteuspto-grants-2012_12