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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194194Generated: November 1, 2026

2-cyclobutylacetic Acid → HCID 59577965, compound

https://huagongshe.com/reaction/2194194

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-cyclobutylacetic AcidHCID 1516411—
ReactantO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
Reactant2-(4-Trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one acetic acid saltHCID 66787333—
ProductHCID 59577965HCID 59577965—

Reaction Steps

The title compound was prepared in analogy to example 13 step A (using TBTU instead of BOP as the coupling reagent) from 2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one acetic acid salt (described in example 180 step C) and cyclobutyl-acetic acid. Off-white solid. MS (ESI): 411.3 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08329904B2
Source datasetuspto-grants-2012_12
ORD IDord-04122d87d2cd4dc6b9b27433a314d25a
Source noteuspto-grants-2012_12