HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → 8-(2-Methyl-thiazole-4-carbonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | 2-Methyl-1,3-thiazole-4-carbonyl chloride | HCID 21183959 | — |
| Edukt | 2-(4-Trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one acetic acid salt | HCID 66787333 | — |
| Produkt | 8-(2-Methyl-thiazole-4-carbonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one | HCID 59577981 | — |
Reaktionsschritte
The title compound was prepared in analogy to example 7 step A from 2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one acetic acid salt (described in example 180 step C) and 2-methyl-thiazole-4-carbonyl chloride; hydrochloride. Off-white solid. MS (ESI): 440.2 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08329904B2 |
| Quelldatensatz | uspto-grants-2012_12 |
| ORD ID | ord-54d40ef29fce442b8fc0c7ec3c14b307 |
| Quellennotiz | uspto-grants-2012_12 |