2-(4-Tert-butylphenyl)ethan-1-amine → HCID 59578005, compound

HRID 2194216Notes

Reaction equation

HRID 2194216 reaction equation
C([O:3][C:4]([C:6]1([CH2:22][CH2:23]OC)[CH2:11][CH2:10][N:9]([S:12]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[Cl:21])(=[O:14])=[O:13])[CH2:8][CH2:7]1)=O)C.[Cl-].C[Al+]C.[C:30]([C:34]1[CH:39]=[CH:38][C:37]([CH2:40][CH2:41][NH2:42])=[CH:36][CH:35]=1)([CH3:33])([CH3:32])[CH3:31]>C1(C)C=CC=CC=1>[C:30]([C:34]1[CH:35]=[CH:36][C:37]([CH2:40][CH2:41][N:42]2[CH2:23][CH2:22][C:6]3([CH2:7][CH2:8][N:9]([S:12]([C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=4[Cl:21])(=[O:13])=[O:14])[CH2:10][CH2:11]3)[C:4]2=[O:3])=[CH:38][CH:39]=1)([CH3:33])([CH3:31])[CH3:32]

Participants

5

Reactant 3

HCID 27356892-(4-Tert-butylphenyl)ethan-1-amineHCID 16686359Dimethylalumanylium chlorideHCID 667876761-(2-Chloro-benzenesulfonyl)-4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 59578005HCID 59578005, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

This material was prepared in analogy to example 1 step D) from 1-(2-chloro-benzenesulfonyl)-4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester, dimethylaluminium chloride in toluene and 2-(4-tert-Butyl-phenyl)-ethylamine. MS (ESI): 489.4 (MH+).

Sources & evidence

ORD record
ord-087812c446a74d43aa41343d3cf902e8
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

Loading…