3,4-Dichlorophenethylamine → HCID 59577998, compound

HRID 2194226Notes

Reaction equation

HRID 2194226 reaction equation
C([O:3][C:4]([C:6]1([CH2:22][CH2:23]OC)[CH2:11][CH2:10][N:9]([S:12]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[Cl:21])(=[O:14])=[O:13])[CH2:8][CH2:7]1)=O)C.[Cl-].C[Al+]C.[Cl:30][C:31]1[CH:32]=[C:33]([CH2:38][CH2:39][NH2:40])[CH:34]=[CH:35][C:36]=1[Cl:37]>C1(C)C=CC=CC=1>[Cl:21][C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=1[S:12]([N:9]1[CH2:8][CH2:7][C:6]2([C:4](=[O:3])[N:40]([CH2:39][CH2:38][C:33]3[CH:34]=[CH:35][C:36]([Cl:37])=[C:31]([Cl:30])[CH:32]=3)[CH2:23][CH2:22]2)[CH2:11][CH2:10]1)(=[O:14])=[O:13]

Participants

5

Reactant 3

HCID 2179583,4-DichlorophenethylamineHCID 16686359Dimethylalumanylium chlorideHCID 667876761-(2-Chloro-benzenesulfonyl)-4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester

Product 1

HCID 59577998HCID 59577998, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

This material was prepared in analogy to example 1 step D) from 1-(2-chloro-benzenesulfonyl)-4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester, dimethylaluminium chloride in toluene and 2-(3,4-Dichloro-phenyl)-ethylamine. MS (ESI): 503.1 (MH+).

Sources & evidence

ORD record
ord-b5039187e1bc46edb766629550f3a041
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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