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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194262Generated: October 30, 2026

Betahistine → HCID 59578104, compound

https://huagongshe.com/reaction/2194262

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBetahistineHCID 2366—
ReactantDiphosgeneHCID 10426—
Reactant2-(4-(Trifluoromethoxy)phenyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 66742759—
ProductHCID 59578104HCID 59578104—

Reaction Steps

This material was prepared in analogy to example 251 step B) from 2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one, diphosgene and methyl-(2-pyridin-2-yl-ethyl)-amine. MS (ESI): 477.4 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08329904B2
Source datasetuspto-grants-2012_12
ORD IDord-58ed43b0b27547f2bc6ad7981fee6618
Source noteuspto-grants-2012_12