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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194266Generated: October 31, 2026

Aniline → 1-Oxo-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-8-sulfonic acid phenylamide

https://huagongshe.com/reaction/2194266

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
Reactant1-Oxo-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-8-sulfonyl chlorideHCID 86647653—
Product1-Oxo-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-8-sulfonic acid phenylamideHCID 59578006—

Reaction Steps

This material was prepared in analogy to example 285 step B) from 1-Oxo-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-8-sulfonyl chloride and phenylamine. MS (ESI): 440.4 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08329904B2
Source datasetuspto-grants-2012_12
ORD IDord-6b23af0473c64f86a325ae58152eb8f0
Source noteuspto-grants-2012_12