2-Phenylpropylamine → HCID 59578046, compound

HRID 2194268Notes

Reaction equation

HRID 2194268 reaction equation
[O:1]=[C:2]1[C:6]2([CH2:11][CH2:10][N:9]([S:12](Cl)(=[O:14])=[O:13])[CH2:8][CH2:7]2)[CH2:5][CH2:4][N:3]1[C:16]1[CH:21]=[CH:20][C:19]([O:22][C:23]([F:26])([F:25])[F:24])=[CH:18][CH:17]=1.[C:27]1([CH:33]([CH3:36])[CH2:34][NH2:35])[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[C:27]1([CH:33]([CH3:36])[CH2:34][NH:35][S:12]([N:9]2[CH2:10][CH2:11][C:6]3([C:2](=[O:1])[N:3]([C:16]4[CH:21]=[CH:20][C:19]([O:22][C:23]([F:26])([F:25])[F:24])=[CH:18][CH:17]=4)[CH2:4][CH2:5]3)[CH2:7][CH2:8]2)(=[O:14])=[O:13])[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1

Participants

3

Reactant 2

HCID 113982-PhenylpropylamineHCID 866476531-Oxo-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-8-sulfonyl chloride

Product 1

HCID 59578046HCID 59578046, compound

Procedure

This material was prepared in analogy to example 285 step B) from 1-Oxo-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-8-sulfonyl chloride and 2-phenyl-propylamine. MS (ESI): 512.5 (MH+).

Sources & evidence

ORD record
ord-854e6bb42ee646bc8e43e585c6dc4fba
Source dataset
uspto-grants-2012_12
Patent number
US08329904B2

Reaction notes

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