HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylbenzeneethanamine → 1-Oxo-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-8-sulfonic acid methyl-phenethyl-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylbenzeneethanamine | HCID 11503 | — |
| Reactant | 1-Oxo-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-8-sulfonyl chloride | HCID 86647653 | — |
| Product | 1-Oxo-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-8-sulfonic acid methyl-phenethyl-amide | HCID 59578051 | — |
Reaction Steps
This material was prepared in analogy to example 285 step B) from 1-Oxo-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-8-sulfonyl chloride and methyl-phenethyl-amine. The reaction was subjected to work-up and purification after stirring for 2 h at room temperature. MS (ESI): 512.5 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329904B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-002c30ee63f8436f92575cd2eb405369 |
| Source note | uspto-grants-2012_12 |