4-(4-Chloromethyl-2-methoxyphenoxymethyl)-2-(2-furyl)-5-methyloxazole → HCID 11649964, compound

HRID 2194302Notes

Reaction equation

HRID 2194302 reaction equation
[CH:1]1[C:13]2[NH:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[C:4]([O:14][CH2:15][C:16]([CH3:21])([CH3:20])[C:17]([OH:19])=[O:18])=[CH:3][CH:2]=1.C1C2NC3C(=CC=CC=3)C=2C(OC(C)(C)C(O)=O)=CC=1.Cl[CH2:43][C:44]1[CH:62]=[CH:61][C:47]([O:48][CH2:49][C:50]2[N:51]=[C:52]([C:56]3[O:57][CH:58]=[CH:59][CH:60]=3)[O:53][C:54]=2[CH3:55])=[C:46]([O:63][CH3:64])[CH:45]=1.ClCC1C=CC(OCC2N=C(C3C=CC=CC=3)OC=2C)=C(OC)C=1>>[O:57]1[CH:58]=[CH:59][CH:60]=[C:56]1[C:52]1[O:53][C:54]([CH3:55])=[C:50]([CH2:49][O:48][C:47]2[CH:61]=[CH:62][C:44]([CH2:43][N:12]3[C:13]4[CH:1]=[CH:2][CH:3]=[C:4]([O:14][CH2:15][C:16]([CH3:21])([CH3:20])[C:17]([OH:19])=[O:18])[C:5]=4[C:6]4[C:11]3=[CH:10][CH:9]=[CH:8][CH:7]=4)=[CH:45][C:46]=2[O:63][CH3:64])[N:51]=1

Participants

5

Reactant 4

HCID 223445974-(4-Chloromethyl-2-methoxyphenoxymethyl)-2-(2-furyl)-5-methyloxazoleHCID 223446094-(4-Chloromethyl-2-methoxyphenoxymethyl)-5-methyl-2-phenyloxazoleHCID 595717393-(9H-carbazole-4-yloxy)-2,2-dimethylpropionic acidHCID 595717422-(9H-carbazole-4-yloxy)-2-methylpropionic acid

Product 1

HCID 11649964HCID 11649964, compound

Procedure

The subject compound was prepared by performing the same operation as that of the example 3 by using 3-(9H-carbazole-4-yloxy)-2,2-dimethylpropionic acid prepared by the reference 30 instead of 2-(9H-carbazole-4-yloxy)-2-methylpropionic acid used in the example 3, and using 4-((4-(chloromethyl)-2-methoxyphenoxy)methyl)-2-(furan-2-yl)-5-methyloxazole prepared by the reference 2 instead of 4-((4-(chloromethyl)-2-methoxyphenoxy)methyl)-5-methyl-2-phenyloxazole.

Workup

  1. customThe subject compound was prepared

Sources & evidence

ORD record
ord-8673080787534cdca09c888279190254
Source dataset
uspto-grants-2012_12
Patent number
US08329913B2

Reaction notes

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