HCID 11713948, compound → HCID 59571724, compound

Participants

Reaction Steps

420 mg of (S)-(+)-2-{9-[3-methoxy-4-(5-methyl-2-phenyl-oxazole-4-ylmethoxy)-benzyl]-9H-carbazole-4-yloxy}butyric acid was suspended in 4.2 mL of ethyl acetate, 125 mg of sodium 2-ethylhexanoate was added thereto, and refluxed for 1 hour. After cooling, the crystalline precipitate was isolated by filtration, washed with ethyl acetate, dried under reduced pressure, and 437 mg of the subject compound was prepared as white crystal. Optical purity 96% ee (HPLC).

Provenance & Evidence