Methyl iodide → HCID 49872484, compound

HRID 2194391Notes

Reaction equation

HRID 2194391 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:22])[N:13]([C:15]3[CH:20]=[CH:19][NH:18][C:17](=[O:21])[CH:16]=3)[CH:14]=2)[CH:5]=[CH:4][N:3]=1.[CH3:23]I>>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:22])[N:13]([C:15]3[CH:20]=[CH:19][N:18]([CH3:23])[C:17](=[O:21])[CH:16]=3)[CH:14]=2)[CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 58111205HCID 58111205, compound

Product 1

HCID 49872484HCID 49872484, compound

Procedure

The title compound, white crystalline solid, MS: m/e=325.2, 327.1 (M+H+), was prepared in accordance with the general method of example 2 from 4-[4-(2-chloro-pyridin-4-ylethynyl)-2-methyl-imidazol-1-yl]-1H-pyridin-2-one and methyl iodide.

Sources & evidence

ORD record
ord-736cac0a64654619a931053ec4d34f59
Source dataset
uspto-grants-2012_12
Patent number
US08334287B2

Reaction notes

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