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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194401Generated: October 30, 2026

2,6-Difluoropyridine → 2-[4-[2-(3-Chlorophenyl)ethynyl]-2-methyl-1H-imidazol-1-yl]-6-fluoropyridine

https://huagongshe.com/reaction/2194401

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-DifluoropyridineHCID 73934—
ReactantHCID 178432693HCID 178432693—
Product2-[4-[2-(3-Chlorophenyl)ethynyl]-2-methyl-1H-imidazol-1-yl]-6-fluoropyridineHCID 58906299—

Reaction Steps

The title compound, off-white cristalline solid, MS: m/e=312.1, 314.1 (M+H+) was prepared in accordance with the general method of example 1b from 4-(3-chloro-phenylethynyl)-2-methyl-1H-imidazole and 2,6-difluoropyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08334287B2
Source datasetuspto-grants-2012_12
ORD IDord-3dc954d3c2ec41b79a846026d80a4578
Source noteuspto-grants-2012_12