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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194422Generated: October 27, 2026

Potassium Hydroxide → 4-(4-iodo-2,5-dimethyl-imidazol-1-yl)-1H-pyridin-2-one

https://huagongshe.com/reaction/2194422

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
Reactant2-Chloro-4-(4-iodo-2,5-dimethyl-imidazol-1-yl)-pyridineHCID 86649886—
Solventtert-ButanolHCID 6386—
Product4-(4-iodo-2,5-dimethyl-imidazol-1-yl)-1H-pyridin-2-oneHCID 66866564—

Reaction Steps

The title compound, white crystalline solid, MS: m/e=315.9 (M+H+), was prepared in accordance with the general method of example 1a from 2-chloro-4-(4-iodo-2,5-dimethyl-imidazol-1-yl)-pyridine and KOH in tert-butanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08334287B2
Source datasetuspto-grants-2012_12
ORD IDord-bd0296c0526843bd96c74bbd1aa89efc
Source noteuspto-grants-2012_12