5-iodo-2,4-dimethyl-1H-imidazole → HCID 86649886, compound

HRID 2194423Notes

Reaction equation

HRID 2194423 reaction equation
[I:1][C:2]1[N:3]=[C:4]([CH3:8])[NH:5][C:6]=1[CH3:7].[Cl:9][C:10]1[CH:15]=[C:14](F)[CH:13]=[CH:12][N:11]=1>>[Cl:9][C:10]1[CH:15]=[C:14]([N:5]2[C:6]([CH3:7])=[C:2]([I:1])[N:3]=[C:4]2[CH3:8])[CH:13]=[CH:12][N:11]=1

Participants

3

Reactant 2

HCID 6136385-iodo-2,4-dimethyl-1H-imidazoleHCID 27827922-Chloro-4-fluoropyridine

Product 1

HCID 86649886HCID 86649886, compound

Procedure

The title compound, white crystalline solid, MS: m/e=329.2, 331.1 (M+H+) was prepared in accordance with the general method of example 1b from 4-iodo-2,5-dimethyl-1H-imidazole (CAS: [631897-38-6]) and 2-chloro-4-fluoropyridine.

Sources & evidence

ORD record
ord-37e467e9d6874aff8c0ab675004f368c
Source dataset
uspto-grants-2012_12
Patent number
US08334287B2

Reaction notes

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