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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194426Generated: November 1, 2026

Iodoethanol → 4-[4-(3-chloro-phenylethynyl)-2,5-dimethyl-imidazol-1-yl]-1-(2-hydroxy-ethyl)-1H-pyridin-2-one

https://huagongshe.com/reaction/2194426

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoethanolHCID 12225—
Reactant4-[4-(3-chloro-phenylethynyl)-2,5-dimethyl-imidazol-1-yl]-1H-pyridin-2-oneHCID 49872578—
Product4-[4-(3-chloro-phenylethynyl)-2,5-dimethyl-imidazol-1-yl]-1-(2-hydroxy-ethyl)-1H-pyridin-2-oneHCID 58111180—

Reaction Steps

The title compound, white crystalline solid, MS: m/e=368.1, 370.1 (M+H+), was prepared in accordance with the general method of example 3 from 4-[4-(3-chloro-phenylethynyl)-2,5-dimethyl-imidazol-1-yl]-1H-pyridin-2-one and 2-iodoethanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08334287B2
Source datasetuspto-grants-2012_12
ORD IDord-90584090e7a047b281a0fbd3509b7691
Source noteuspto-grants-2012_12