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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194428Generated: October 31, 2026

3-Methylphenylacetylene → 4-(2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl)-1H-pyridin-2-one

https://huagongshe.com/reaction/2194428

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethylphenylacetyleneHCID 136600—
Reactant4-(4-iodo-2,5-dimethyl-imidazol-1-yl)-1H-pyridin-2-oneHCID 66866564—
Product4-(2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl)-1H-pyridin-2-oneHCID 58111189—

Reaction Steps

The title compound, light brown solid, MS: m/e=304.1 (M+H+), was prepared in accordance with the general method of example 21a from 4-(4-iodo-2,5-dimethyl-imidazol-1-yl)-1H-pyridin-2-one and 1-Ethynyl-3-methyl-benzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08334287B2
Source datasetuspto-grants-2012_12
ORD IDord-fb7ab7e32a3f485abea098a2ce2b2dc4
Source noteuspto-grants-2012_12