Methyl iodide → 4-[2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl]-1-methyl-1H-pyridin-2-one

HRID 2194429Notes

Reaction equation

HRID 2194429 reaction equation
[CH3:1][C:2]1[N:3]([C:17]2[CH:22]=[CH:21][NH:20][C:19](=[O:23])[CH:18]=2)[C:4]([CH3:16])=[C:5]([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=2)[N:6]=1.[CH3:24]I>>[CH3:1][C:2]1[N:3]([C:17]2[CH:22]=[CH:21][N:20]([CH3:24])[C:19](=[O:23])[CH:18]=2)[C:4]([CH3:16])=[C:5]([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=2)[N:6]=1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 581111894-(2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl)-1H-pyridin-2-one

Product 1

HCID 498727644-[2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl]-1-methyl-1H-pyridin-2-one

Procedure

The title compound, brown solid, MS: m/e=318.2 (M+H+), was prepared in accordance with the general method of example 3 from 4-[2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl]-1H-pyridin-2-one and methyl iodide.

Sources & evidence

ORD record
ord-bc16341ecbdb487bba1f2b848fae2926
Source dataset
uspto-grants-2012_12
Patent number
US08334287B2

Reaction notes

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