Methyl iodide → 6-(4-iodo-2,5-dimethyl-imidazol-1-yl)-3-methyl-3H-pyrimidin-4-one
Reaction equation
[I:1][C:2]1[N:3]=[C:4]([CH3:15])[N:5]([C:8]2[N:13]=[CH:12][NH:11][C:10](=[O:14])[CH:9]=2)[C:6]=1[CH3:7].[CH3:16]I>>[I:1][C:2]1[N:3]=[C:4]([CH3:15])[N:5]([C:8]2[N:13]=[CH:12][N:11]([CH3:16])[C:10](=[O:14])[CH:9]=2)[C:6]=1[CH3:7]Participants
3
Procedure
The title compound, light yellow cristalline solid, MS: m/e=331.0 (M+H+), was prepared in accordance with the general method of example 3 from 6-(4-iodo-2,5-dimethyl-imidazol-1-yl)-3H-pyrimidin-4-one and methyl iodide.
Sources & evidence
- ORD record
- ord-115064a3d5db4ed39573e9a370545f14
- Source dataset
- uspto-grants-2012_12
- Patent number
- US08334287B2
Reaction notes
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