4,5-dichloro-2-ethyl-3(2H)-pyridazinone → 4-Chloro-2-ethyl-5-methoxy-3(2H)-pyridazinone

HRID 2194455Notes

Reaction equation

HRID 2194455 reaction equation
[Cl:1][C:2]1[C:3](=[O:11])[N:4]([CH2:9][CH3:10])[N:5]=[CH:6][C:7]=1Cl.[CH3:12][O-:13].[Na+]>CO>[Cl:1][C:2]1[C:3](=[O:11])[N:4]([CH2:9][CH3:10])[N:5]=[CH:6][C:7]=1[O:13][CH3:12]

Participants

4

Reactant 2

HCID 6764264,5-dichloro-2-ethyl-3(2H)-pyridazinoneHCID 10942334Sodium Methoxide

Product 1

HCID 106552464-Chloro-2-ethyl-5-methoxy-3(2H)-pyridazinone

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The title compound, white crystalline solid, was prepared in accordance with the general method of example 23e by treatment of 4,5-dichloro-2-ethyl-2H-pyridazin-3-one with sodium methoxide in methanol.

Sources & evidence

ORD record
ord-97306542f82f4296ba637ea0cfdd4b0b
Source dataset
uspto-grants-2012_12
Patent number
US08334287B2

Reaction notes

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