5-chloro-2-(2-methoxyethyl)pyridazin-3(2H)-one → 2-(2-methoxy-ethyl)-5-(4-iodo-2-methyl-imidazol-1-yl)-2H-pyridazin-3-one

HRID 2194460Notes

Reaction equation

HRID 2194460 reaction equation
Cl[C:2]1[CH:7]=[N:6][N:5]([CH2:8][CH2:9][O:10][CH3:11])[C:4](=[O:12])[CH:3]=1.[I:13][C:14]1[N:15]=[C:16]([CH3:19])[NH:17][CH:18]=1>>[CH3:11][O:10][CH2:9][CH2:8][N:5]1[C:4](=[O:12])[CH:3]=[C:2]([N:17]2[CH:18]=[C:14]([I:13])[N:15]=[C:16]2[CH3:19])[CH:7]=[N:6]1

Participants

3

Reactant 2

HCID 668667375-chloro-2-(2-methoxyethyl)pyridazin-3(2H)-oneHCID 178433060HCID 178433060, compound

Product 1

HCID 668651282-(2-methoxy-ethyl)-5-(4-iodo-2-methyl-imidazol-1-yl)-2H-pyridazin-3-one

Procedure

The title compound, light yellow oil, MS: m/e=361.1 (M+H+), was prepared in accordance with the general method of example 23b from 5-chloro-2-(2-methoxy-ethyl)-2H-pyridazin-3-one and 4-Iodo-2-methyl-1H-imidazole.

Sources & evidence

ORD record
ord-b3943155cde34366949224b41547213e
Source dataset
uspto-grants-2012_12
Patent number
US08334287B2

Reaction notes

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