5-iodo-2,4-dimethyl-1H-imidazole → 5-(4-Iodo-2,5-dimethyl-imidazol-1-yl)-2-(2-methoxy-ethyl)-2H-pyridazin-3-one

HRID 2194467Notes

Reaction equation

HRID 2194467 reaction equation
Cl[C:2]1[CH:7]=[N:6][N:5]([CH2:8][CH2:9][O:10][CH3:11])[C:4](=[O:12])[CH:3]=1.[I:13][C:14]1[N:15]=[C:16]([CH3:20])[NH:17][C:18]=1[CH3:19]>>[I:13][C:14]1[N:15]=[C:16]([CH3:20])[N:17]([C:2]2[CH:7]=[N:6][N:5]([CH2:8][CH2:9][O:10][CH3:11])[C:4](=[O:12])[CH:3]=2)[C:18]=1[CH3:19]

Participants

3

Reactant 2

HCID 6136385-iodo-2,4-dimethyl-1H-imidazoleHCID 66866737HCID 66866737, compound

Product 1

HCID 668657305-(4-Iodo-2,5-dimethyl-imidazol-1-yl)-2-(2-methoxy-ethyl)-2H-pyridazin-3-one

Procedure

The title compound, light yellow waxy solid, MS: m/e=375.2 (M+H+), was prepared in accordance with the general method of example 23b from 5-Chloro-2-(2-methoxy-ethyl)-2H-pyridazin-3-one and 4-iodo-2,5-dimethyl-1H-imidazole.

Sources & evidence

ORD record
ord-3b6829cd1dd64559be625a72a6632f19
Source dataset
uspto-grants-2012_12
Patent number
US08334287B2

Reaction notes

Loading…