[2-(Methylamino)pyridin-3-yl]methanol → 2-(methylamino)nicotinaldehyde

Participants

Reaction Conditions

Reaction Steps

9.10 g (66.0 mmol) of (2-(methylamino)-3-pyridinyl)methanol was dissolved in chloroform (70 mL), and 17.4 g (200 mmol) of manganese dioxide was added thereto. The mixture was stirred overnight at 60° C. The reaction mixture was filtered, and the filtrate was concentrated. Thus, 8.66 g (yield: 96%) of the title compound was obtained as an orange-colored solid.

Provenance & Evidence