HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenoxybenzoic acid → N-(5-Hydroxymethyl-adamantan-2-yl)-3-phenoxy-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenoxybenzoic acid | HCID 19539 | — |
| Reactant | 4-Aminotricyclo[3.3.1.13,7]decane-1-methanol | HCID 57928167 | — |
| Product | N-(5-Hydroxymethyl-adamantan-2-yl)-3-phenoxy-benzamide | HCID 25108929 | — |
Reaction Steps
Prepared from 3-phenoxy benzoic acid and 4-amino-1-hydroxymethyladamantane to give the title compound as a mixture of two isomers. 1H NMR (400 MHz, CDCl3) δ: 7.31-7.49 (m, 5H), 7.08-7.18 (m, 2H), 7.02 (d, 2H), 6.29-6.43 (m, 1H), 4.13-4.23 (m, 1H), 3.24 (d, 2H), 2.09-2.18 (m, 2H), 2.01 (br. s., 1H), 1.55-1.92 (m, 10H), 1.44 (d, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08334305B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-abf0a006e801412c9e3a2ca4ee59e3e5 |
| Source note | uspto-grants-2012_12 |