HCID 19432606, compound → HCID 25254528, compound

Participants

Reaction Steps

Example 26a (47 mg, 0.136 mmol) was reacted with 2-(pyridin-2-yl)ethyltrifluoromethanesulphonate (0.3 mL) according to General Procedure F to give the title compound (38 mg, 60%). 1H NMR (300 MHz, CDCl3) δ 8.54 (dd, 1H), 7.57 (t, 1H), 7.28-7.08 (m, 7H), 4.09 (t, J=6.3 Hz, 2H), 3.75 (s, 3H), 3.11 (t, J=6.3 Hz, 2H), 2.54 (t, J=6.9 Hz, 2H), 2.44 (t, J=6.9 Hz, 2H), 2.35 (s, 3H), 2.18 (s, 3H), 1.56-1.43 (m, 4H).

Provenance & Evidence