Acetyl bromide → HCID 67050506, compound

Participants

Reaction Conditions

Reaction Steps

In a 10 mL round bottom flask, 1 mL AcBr was added to 3-(5-Isopropyl-2,6-dimethoxy-pyrimidin-4-yl)-quinoline (14 mg, 0.045 mmol). The reaction mixture was heated at 70° C. for 2 hours. The reaction mixture was concentrated down and purified by reverse phase prep HPLC (MeCN/water) to give a white powder (6 mg, 47%). LC-MS shows 280.3 (M−1).

Provenance & Evidence