反应详情

温度

77.5 °C

Uncoated Dextromethorphan Resin Complex was prepared by first dissolving 119.28 g of dextromethorphan HBr in 1 L of purified water heated to 75-80° C., followed by the addition of 223.01 g AMBERLITE IRP-69 resin under gentle mixing for 4 hours. At the completion, the suspension was allowed to settle, and was then decanted and rinsed with purified water twice and dried in an oven maintained at 50° C. until the moisture content was around 5%. The dried resin complex was hand sieved through a 40 mesh screen.

1. additionfollowed by the addition of 223.01 g AMBERLITE IRP-69 resin
2. additionunder gentle mixing for 4 hours
3. customwas then decanted
4. washrinsed with purified water twice
5. customdried in an oven
6. temperaturemaintained at 50° C. until the moisture content
7. filtrationsieved through a 40 mesh screen