HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Indanol → 6-Bromo-7-hydroxychroman-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Indanol | HCID 77936 | — |
| Reactant | 6-Bromo-7-(2,3-dihydro-1H-inden-2-yloxy)chroman-2-one | HCID 66877022 | — |
| Product | 6-Bromo-7-hydroxychroman-2-one | HCID 46835416 | — |
| Product | 6-Bromo-7-(2,3-dihydro-1H-inden-2-yloxy)chroman-2-one | HCID 66877022 | — |
Reaction Steps
6-Bromo-7-(2,3-dihydro-1H-inden-2-yloxy)chroman-2-one (1.25 g, Intermediate 5) can be obtained from Intermediate 2 (1.0 g) and 2-hydroxyindane (henceforth abbreviated as “sm5”, 830 mg, LANC) according to the method of Example 1-1-2, Step B. The title compound was obtained (yield: 690 mg) from Intermediate 5 (500 mg) according to the method of Example 1-1-2, Step C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08334314B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-bf8923ebb9cd49b4b1e05c5146b4dd72 |
| Source note | uspto-grants-2012_12 |