Water → HCID 57089504, compound

HRID 2194956Notes

Reaction equation

HRID 2194956 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:11]2[CH:17]=[CH:16][C:14]([NH2:15])=[CH:13][CH:12]=2)[CH:7]=[CH:8][C:9]=1[NH2:10])([O-:3])=[O:2].[CH2:18]([O:20][C:21](Cl)=[O:22])[CH3:19].[OH2:24]>C(O)C>[C:21]([NH:10][C:9]1[CH:8]=[CH:7][C:6]([C:11]2[CH:17]=[CH:16][C:14]([NH:15][C:21]([O:20][CH2:18][CH3:19])=[O:24])=[CH:13][CH:12]=2)=[CH:5][C:4]=1[N+:1]([O-:3])=[O:2])([O:20][CH2:18][CH3:19])=[O:22]

Participants

5

Reactant 3

HCID 962WaterHCID 10928Ethyl chloroformateHCID 40471313-Nitrobenzidine

Product 1

HCID 57089504HCID 57089504, compoundYield 95%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

Twenty nine grams 3-nitrobenzidine were dissolved in 330 ml ethanol containing 39 ml (36 grams) dimethyaniline. Thirty one grams ethylchloroformate were added to the ethanol solution in portions. The solution was then refluxed for 10 minutes after which water was added to precipitate the diurethane derivative. Forty one grams were obtained corresponding to a yield of 95%.

Workup

  1. additionwas added
  2. customto precipitate the diurethane derivative
  3. customForty one grams were obtained corresponding to a yield of 95%

Sources & evidence

ORD record
ord-0d773d82626543be9a673def0ba476ed
Source dataset
uspto-grants-2012_12
Patent number
US08334370B1

Reaction notes

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