HCID 86642401, compound → 1-Ethynyl-1-methoxycyclohexane
Reaction equation
[C:1]([C:3]1([O:10][CH3:11])[CH2:8][CH2:7]N(C)[CH2:5][CH2:4]1)#[CH:2].[CH:12]1(N2CCC(C#C)(OC)CC2)CCCC1>>[C:1]([C:3]1([O:10][CH3:11])[CH2:8][CH2:7][CH2:12][CH2:5][CH2:4]1)#[CH:2]Participants
3
Procedure
4-Ethynyl-4-methoxy-1-methyl-piperidine and 1-cyclopentyl-4-ethynyl-4-methoxypiperidine may be prepared analogously.
Sources & evidence
- ORD record
- ord-ac97e44506dd4cdeac1ef57c1b82aafb
- Source dataset
- uspto-grants-2012_12
- Patent number
- US08334378B2
Reaction notes
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