Dichloromethane → HCID 66853922, compound

HRID 2195009Notes

Reaction equation

HRID 2195009 reaction equation
[O:1]=[C:2]1[C:15]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[N:9]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][C:21]([NH:23][CH2:24][CH2:25][NH:26]C(=O)OC(C)(C)C)=[O:22])[C:8]2[C:3]1=[CH:4][CH:5]=[CH:6][CH:7]=2.C(Cl)[Cl:35]>>[ClH:35].[NH2:26][CH2:25][CH2:24][NH:23][C:21](=[O:22])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][N:9]1[C:8]2[C:3](=[CH:4][CH:5]=[CH:6][CH:7]=2)[C:2](=[O:1])[C:15]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]1=2

Participants

3

Reactant 2

HCID 6344DichloromethaneHCID 58939869HCID 58939869, compound

Product 1

HCID 66853922HCID 66853922, compound

Procedure

To 0.30 g of tert-butyl 2-{[6-(9-oxoacridin-10(9H)-yl)hexanoyl]amino}ethylcarbamate was added dicholoromethane (DCM; 30 ml). HCl (g) was bubbled through the solution for 10 minutes. After this time the mixture was filtered and washed with DCM (3×20 ml) to give the desired product (0.15 g; Formula XIX). Mass spectrum: 352 (M+H).

Workup

  1. customHCl (g) was bubbled through the solution for 10 minutes
  2. filtrationAfter this time the mixture was filtered
  3. washwashed with DCM (3×20 ml)

Sources & evidence

ORD record
ord-a2f2c995d8d443919bf5a2c126e9d1a5
Source dataset
uspto-grants-2012_12
Patent number
US08334387B2

Reaction notes

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