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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2195376Generated: October 30, 2026

Ethanolamine → HCID 22060429, compound

https://huagongshe.com/reaction/2195376

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolamineHCID 700—
ReactantHCID 22061087HCID 22061087—
ProductHCID 22060429HCID 22060429—

Reaction Steps

In like manner to the preparation of N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-[3-(N-morpholinoethyleneamino)carbonylmethyleneaminophenyl]-2,4-pyrimidinediamine, N2-(3-ethoxycarbonylmethyleneaminophenyl)-5-fluoro-N4-(3-hydroxyphenyl)-2,4-pyrimidinediamine and 2-aminoethanol were reacted to prepare 5-fluoro-N4-(3-hydroxyphenyl)-N2-[3-(N2-hydroxyethylamino)carbonylmethyleneaminophenyl]-2,4-pyrimidinediamine. LCMS: ret. time: 13.28 min.; purity: 97.3%; MS (m/e): 413.04 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08334296B2
Source datasetuspto-grants-2012_12
ORD IDord-e392591e71f740c59e756cd9a9f452f3
Source noteuspto-grants-2012_12