Acetic Acid → HCID 59435072, compound

Participants

Reaction Conditions

Reaction Steps

3,4-bis(2,2-dimethoxy-1,3-dioxoindan-5-yl)thiophene (36) (178 mg, 0.361 mmol) was suspended in a solvent mixture of 2 ml of acetic acid and 2 ml of water, and the suspension was mixed with 2 ml of 47% hydrobromic acid. The mixture was refluxed at 110° C. for 1.5 hours. After it was cooled to room temperature, the reaction solution was diluted with water and then left all day and night to obtain a solid. The solid was filtered, washed with water, and dried, to obtain 68 mg (43%) of 3,4-bis(2,2-dihydroxy-1,3-dioxoindan-5-yl)thiophene (37) in the form of a beige solid. The readings for this compound are as follows.

Provenance & Evidence