Benzylamine → HCID 86641242, compound

Participants

Reaction Steps

a method, wherein the amino group of L-aspartic acid is protected, the carboxy group is reduced, the resulting hydroxyl group is converted into a leaving group, the resultant is reacted with ammonia to produce (S)-3-(tert-butoxycarbonyloxyamino) piperidine, the piperidine is reacted with benzylamine instead of ammonia to obtain (S)-1-benzyl-3-(tert-butoxycarbonyloxyamino) piperidine, and deprotection is carried out using trifluoroacetic acid to produce (S)-1-benzyl-3-aminopiperidine (Non-patent Document 3).

Provenance & Evidence