Isoniazid → HCID 86606228, compound

HRID 2195681Notes

Reaction equation

HRID 2195681 reaction equation
[C:1]([C:4]1[C:5](=[O:17])[O:6][C:7]2[C:12]([CH:13]=1)=[C:11]([CH3:14])[CH:10]=[C:9]([O:15][CH3:16])[CH:8]=2)([OH:3])=O.[CH:18]1[C:23]([C:24]([NH:26][NH2:27])=[O:25])=[CH:22][CH:21]=[N:20][CH:19]=1>>[C:24]([NH:26][NH:27][C:1]([C:4]1[C:5](=[O:17])[O:6][C:7]2[C:12]([CH:13]=1)=[C:11]([CH3:14])[CH:10]=[C:9]([O:15][CH3:16])[CH:8]=2)=[O:3])(=[O:25])[C:23]1[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 3767IsoniazidHCID 23085540HCID 23085540, compound

Product 1

HCID 86606228HCID 86606228, compound

Procedure

Compound 213 was prepared following the preparation of compound 26 except that 3-carboxy-5-methyl-7-methoxy-coumarin reacted with isoniazid to give the title compound 213.

Workup

  1. customCompound 213 was prepared

Sources & evidence

ORD record
ord-be37b253a9a94e9fa62a80ac0da5b309
Source dataset
uspto-grants-2012_12
Patent number
US08338401B2

Reaction notes

Loading…