HuagongsheHuagongshe Chemistry Print Report · For research reference only
Amino 4-methylbenzene-1-sulfonate → HCID 86644590, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Amino 4-methylbenzene-1-sulfonate | HCID 10965249 | — |
| Reactant | 2-Amino-3-cyano-4-benzylamino-6-morpholino-quinoline | HCID 11674888 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86644590 | HCID 86644590 | — |
Reaction Steps
To the solution of 3 g 2-amino-3-cyano-4-benzylamino-6-morpholino-quinoline in 20 ml dimethylformamide, 2.2 g of O-tosylhydroxylamine dissolved in 25 ml dichloromethane is added dropwise at 20° C. in 15 minutes. After 5 hours of stirring the precipitated crystalline material is filtered off. After drying 3.8 g of the title compound is obtained (MH+:376).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338411B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-b7d73b914eae46f08b0e44611fdd7a91 |
| Source note | uspto-grants-2012_12 |