HCID 59198061, compound → HCID 59198082, compound

Participants

Reaction Steps

N3-[4-(5-Methoxy-pyridin-3-yl)-pyrimidin-2-yl]-4-methyl-benzene-1,3-diamine 14 is prepared by hydrogenation of 13 using a similar protocol for the preparation of 10. 1H NMR (400 MHz, d6-DMSO) δ 8.90 (d, J=1.6 Hz, 1H), 8.71 (s, 1H), 8.51 (d, J=5.2 Hz, 1H), 8.45 (d, J=2.8 Hz, 1H), 8.01 (dd, J=2.0, 3.2 Hz, 1H), 7.43 (d, J=5.2 Hz, 1H), 6.91 (d, J=8.0 Hz, 1H), 6.87 (d, J=2.4 Hz, 1H), 6.38 (dd, J=2.4, 8.0 Hz, 1H), 4.87 (s, 2H), 3.95 (s, 3H), 2.12 (s, 3H). MS (m/z) (M+1)+: 308.1

Provenance & Evidence