Acetic Anhydride → HCID 67130140, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 5-(2-amino-3H-benzimidazol-5-yl)-furan-2-carboxylic acid ((S)-cyclohexyl-methylcarbamoyl-methyl)-amide (10 mg, 0.025 mmol) in anhydrous pyridine (1 mL) is added acetic anhydride. The mixture is heated at 100° C. for 2 h. After cooling to room temperature the mixture is purified by reversed phase (HPLC). 4.6 mg, 42%, LC/MS ESI m/z (M+H)+=438.47.

Provenance & Evidence